Regenerative medicine is a branch translational research which deals with the process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function. Regenerative orthopaedics is a subspecialty of regenerative medicine that focuses on regeneration of lost tissue, acceleration of healing, and pain relief to treat orthopaedic conditions such as osteoarthritis, tendonitis, low back pain, joint injuries (degenerative arthritis), ligament injuries, sprains and strains etc. Regenerative orthopaedics uses: • Mesenchymal Stem Cells that are usually obtained from the bone marrow or fat. • Platelets: Platelets obtained from blood • Growth factors: Proteins obtained from blood that are essential for tissue repair and regeneration Regenerative orthopaedics is used to avoid or delay surgery, accelerate healing after surgery or injury, or when surgery or other therapies have failed. When it comes to Regenerative Orthopaedics…… “The future and the future is now”.
Medical Shockwave Treatment
Medical Shockwave Treatment is a relatively new non-invasive therapeutic modality with effectiveness, convenience and safety, and has the potential of replacing surgery in many orthopaedic disorders without surgical risks. In the past 10 to 15 years shockwave treatment had emerged as the leading choice in the treatment of many orthopaedic disorders including plantar fasciitis, lateral epicondylitis, patella and Achilles tendinopathies, calcific tendinitis of the shoulder and non-union of long bone fractures. The exact mechanism of shockwave treatment remains unknown however it is thought that it induces a cascade of biological responses and molecular changes including the ingrowth of vascularization and up-regulation of angiogenetic growth factors leading to the improvement in blood supply inducing tissues repair and regeneration. The vast majority of published papers show a positive beneficial effect and clinical application of shockwave treatment will increase in the coming years.
Ultrasound scanning is a powerful tool for imaging joint and soft tissue pathology and fast becoming an integral part of routine diagnosis and management in Musculoskeletal (MSK) Medicine. An increasing number of clinicians involved in Regenerative Orthopaedics that when injuries are being considered, the clinical examination process should be “look, feel, move and ultrasound”. There are many advantages with ultrasound with diagnostic ultrasound compared to other imaging modalities. First, U/S is estimated to be less expensive than MRI, patient friendly as claustrophobia is not encountered with U/S. Ultrasound can also detect several anatomical regions that may be clinically unrelated to the patient’s complaint. Clinician can also interact with the patient who can direct the examination toward the symptomatic area Since the U/S exam is real time, the patient and even the physician can receive results immediately and then outline a treatment strategy within the same visit. Many specialties such as Sports Medicine, Rheumatology, Orthopaedics, and Family Practice are integrating this imaging modality into their daily practices.